WHITE PAPER
Deciphering Glioma Patient Subpopulations Using NetraAI: Exploring an Association to Human Papillomavirus (HPV)
Currently, oligodendrogliomas (OGs) are stratified into three molecular subgroups on the basis of IDH mutation and 1p/19q co-deletion. Amongst 1p/19q co-deleted OG tumors, there is molecular heterogeneity related to EGFR, PTEN, 10q deletion, and several other markers...
Leveraging Large Language Models with NetraAI for Clinical Trial De-Risking: Launching NetraGPT
NetraAI represents a distinctive, Good Clinical Practice (GCP)-authenticated machine learning architecture that offers an accessible interface for researchers to engage with consolidated multimodal datasets. This empowers sponsors to uncover explainable patient...
Hypothesis Generation Using NetraAI Reveals Genetic Drivers of Non-Small Cell Lung Cancer
Non-small cell lung cancer (NSCLC) accounts for 85% of all lung cancers and can be divided into three histological subtypes with distinct presentation and prognoses: adenocarcinoma (ADC), squamous cell carcinoma (SCC), and large cell carcinoma (LCC).1 In addition to...
Discovery of Unique Genetic Subtypes Contributing to Heterogeneity in Alzheimer’s Disease Progression Using NetraAI
Alzheimer’s disease (AD) is a neurodegenerative disease that contributes to 60-70% of all dementia cases and is characterized by neuronal cell damage and cognitive decline.1 Currently, drugs for AD target symptom control and there is no effective curative therapy for...
Drug and Placebo Response Modeling Using Assessment Data with NetraAI
Clinical scale patient reported outcomes are commonly used research tools that can be designed to provide quantitative or qualitative outputs. These assessments use objective scales and/or qualitative, open-ended responses that rely on self-reporting to collect...
Leveraging NetraAI to Identify Novel Insights for Pancreatic Cancer Patient Response to Therapy
Challenges with Pancreatic Cancer Pancreatic cancer is deemed the “silent killer” due to vague symptoms, late diagnosis, rapid progression, and poor response to therapy. As the 14th most common cancer but 7th leading cause of cancer-associated deaths, prolonging...